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1.  Study Posting (2348) Trial #50072, Obsessive-Compulsive Disorders, New York, NY
...Posting (2348) Trial #50072, Obsessive-Compulsive Disorders, New York, NY Trial Information Ziprasidone augmentation in serotonin reuptake inhibitor-resistant Obsessive-Compulsive Disorder The purpose of this study is to determine whether the medication ziprasidone (Geodon) added to a serotonin reuptake inhibitor (SRI) is effective in the treatment of patients who have previously experienced little ...
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2.  Study Posting (799) Trial #161750, Depression, Boston, MA
...Study Posting (799) Trial #161750, Depression, Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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3.  Study Posting (799) Trial #159744, Depression, Boston, MA
...Study Posting (799) Trial #159744, Depression, Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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4.  Study Posting (799) Trial #156617, Depression, Boston, MA
...Study Posting (799) Trial #156617, Depression, Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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5.  Study Posting (799) Trial #161751, Depression (Treatment-Resistant), Boston, MA
...Posting (799) Trial #161751, Depression (Treatment-Resistant), Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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6.  Study Posting (799) Trial #161733, Depression (Major/Severe), Boston, MA
...Posting (799) Trial #161733, Depression (Major/Severe), Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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7.  Study Posting (799) Trial #159734, Depression (Major/Severe), Boston, MA
...Posting (799) Trial #159734, Depression (Major/Severe), Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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8.  Study Posting (799) Trial #156606, *Healthy Patient Studies, Boston, MA
...Posting (799) Trial #156606, *Healthy Patient Studies, Boston, MA combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI)<br/>Escitalopram for patients with Major Depressive Disorder (MDD) that do not ...
...to test the efficacy, tolerability and safety of the combination of Ziprasidone with the selective serotonin reuptake inhibitor (SSRI) Escitalopram for patients with Major Depressive Disorder (MDD) that do not sufficiently ...
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9.  Study Posting (2348) Trial #53934, Body Dysmorphic Disorder, New York, NY
...Body Dysmorphic Disorder, New York, NY Trial Information Cognitive-Behavioral Therapy as an Adjunct to Serotonin Reuptake Inhibitors in the Treatment of Body Dysmorphic Disorder The purpose of this study is ...
...of BDD. The program we are currently offering is a 2-phase study using a serotonin reuptake inhibitor (SRI) medication called Effexor in addition to psychotherapy. The first phase of the ...
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10.  Study Posting (799) Trial #156909, Depression (Major/Severe), Boston, MA
...Boston, MA Trial Information The Efficacy and Tolerability of Seroquel XR Combined with a Selective Serotonin Re-Uptake Inhibitor versus Seroquel XR Monotherapy in the Acute Treatment of Major Depressive Disorder ...
...com rseabrook@partners.org The Efficacy and Tolerability of Seroquel XR Combined with a Selective Serotonin Re-Uptake Inhibitor versus Seroquel XR Monotherapy in the Acute Treatment of Major Depressive Disorder ...
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11.  Newly Approved Drug Therapies (713) Kytril (granisetron) solution, Roche,
...Kytril is currently available in both tablet and injection formulations. Kytril works by blocking the serotonin 5-HT3 receptor. When a subjects receives chemotherapy, the hormone serotonin is released by cells in the small intestine. Serotonin acts on the vagus nerve to ...
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12.  Newly Approved Drug Therapies (998) Sancuso (granisetron), ProStrakan,
...transdermal elective 5-hydroxytryptamine3 (5-HT3) receptor antagonist with little or no affinity for other serotonin receptors. During chemotherapy that induces vomiting, mucosal enterochromaffin cells release serotonin, which stimulates 5-HT3 receptors. The 5-HT3 antagonists prevent serotonin from binding to 5 ...
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13.  Newly Approved Drug Therapies (1012) Savella (milnacipran hydrochloride), Forest Laboratories,
...Approval Status: Approved January 2009 Treatment Area: fibromyalgia General Information Savella (milnacipran) is a selective serotonin and norepinephrine reuptake inhibitor. It affects the two neurotransmittersalmost equally (a 3:1 norepinephrine to serotonin balance). However, the exact mechanism of the central pain inhibitory action of milnacipran and its ...
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14.  News: Cymbalta Reduces Pain in Fibromyalgia Trial (Clinical Trials Today)
...phase III trial of Cymbalta (duloxetine) for the treatment of fibromyalgia. Cymbalta is Lilly’s serotonin and norepinephrine reuptake inhibitor (SSNRI), approved in the U.S. for major depression and diabetic ...
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15.  CenterWatch: New Medical Therapies in Disease Category (7), Affective Disorders
...results from a phase I trial investigating SGS518 , a selective antagonist of the 5-HT6 serotonin receptor for the treatment of Cognitive Impairment Associated with Schizophrenia (CIAS). The drug is thought ...
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16.  Newly Approved Drug Therapies (685) Prozac Weekly (fluoxetine HCl), Eli Lilly,
...an enteric coating that delays release into the bloodstream. Fluoxetine is known as a selective serotonin reuptake inhibitor - it is believed to provide a therapeutic effect by blocking neuronal (nerve cell) uptake of serotonin, resulting in increased levels of the hormone. Major depressive disorders, which include depression, affect an ...
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17.  Study Posting (709) Trial #116328, Depression, Stanford, CA
...is to get information on the effectiveness of switching to duloxetine (Cymbalta) from a selective serotonin reuptake inhibitor (SSRI) to relieve sexual dysfunction in patients with depression. Duloxetine has been approved ...
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18.  Newly Approved Drug Therapies (865) Cymbalta (duloxetine), Eli Lilly,
...duloxetine hydrochloride) is a oral dual reuptake inhibitor that enhances the levels of the neurotransmitters, serotonin and norepinephrine, which are involved in depression. Cymbalta is indicated for the treatment of major ...
...duloxetine hydrochloride) is a oral dual reuptake inhibitor that enhances the levels of the neurotransmitters, serotonin and norepinephrine, which are involved in depression. Duloxetine is also believed to affect stress urinary ...
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19.  Study Posting (709) Trial #116327, Sexual Dysfunction, Stanford, CA
...is to get information on the effectiveness of switching to duloxetine (Cymbalta) from a selective serotonin reuptake inhibitor (SSRI) to relieve sexual dysfunction in patients with depression. Duloxetine has been approved ...
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20.  Newly Approved Drug Therapies (706) Axert (almotriptan malate) tablets, Pharmacia,
...or without aura in adults. Axert belongs to a class of drugs known as selective serotonin receptor agonists. These drugs target serotonin receptors and act against migraine headaches by inducing the constriction of blood vessels surrounding the ...
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