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1.  Newly Approved Drug Therapies (655) Trizivir (abacavir sulfate; lamivudine; zidovudine AZT) Tablet, GlaxoSmithKline,
...Newly Approved Drug Therapies (655) Trizivir (abacavir sulfate; lamivudine; zidovudine AZT) Tablet, GlaxoSmithKline, Drug Information The following information is obtained from various newswires, published medical journal articles, and medical conference presentations. Drug Name: Trizivir (abacavir sulfate; lamivudine; zidovudine AZT) Tablet Company: GlaxoSmithKline Approval Status: Approved November 2000 Treatment Area: HIV Infection General Information ...
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2. Clinical Trial Results by Drug Names
...naïve patients to assess the efficacy and safety of enfuvirtide in combination with lamivudine and zidovudine in the acute phase, compared to a standard treatment with lopinavir/ritonavir in combination with lamivudine and zidovudine. The acute phase was followed by a maintenance phase. Study center(s) : 7 centers in ...
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3. Clinical Trial Results by Drug Names
...NR15691 evaluated potential drug interactions between ribavirin and two nucleoside reverse transcriptase inhibitor (NRTI) regimens (zidovudine plus lamivudine and stavudine plus lamivudine) administered concomitantly with ribavirin or placebo in combination with ...
...Primary: To examine in vivo ribavirin's effect on the intracellular phosphorylation of the NRTIs zidovudine, lamivudine, and/or stavudine in chronic hepatitis C (CHC) patients coinfected with HIV. Secondary: (1 ...
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4.  Newly Approved Drug Therapies (835) Reyataz (atazanavir sulfate), Bristol-Myers Squibb,
...Reyataz (400mg) to efavirenz (600mg) once daily, each in combination with fixed-dose lamivudine (150) + zidovudine (300mg) twice daily. The study enrolled 810 antiretroviral treatment-naive subjects for 48 weeks. Subject ...
...and 65% were male. Result showed that 67% of subjects in the Reyataz plus lamivudine/zidovudine group responded to treatment compared with 62% of subjects in the efavirenz plus lamivudine/zidovudine ...
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5.  Newly Approved Drug Therapies (64) Crixivan (Indinavir sulfate), Merck,
...One recent multicenter trial studied Crixivan alone and in combination with two other antiviral drugs, zidovudine and lamivudine (Retrovir and Epivir) in subjects who had previously been treated with zidovudine. At 24 weeks in this "triple-therapy" trial, mean decreases observed in viral load were ...
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6.  Newly Approved Drug Therapies (39) Zerit (stavudine), Bristol-Myers Squibb,
...438 subjects participated in a randomized, double-blind, 12-week clinical trial comparing Zerit to zidovudine, another treatment for HIV infection. Subjects receiving Zerit had a mean increase in CD4+ cell count from baseline to week 12, while subjects continuing on zidovudine had a mean decrease of CD4+ cell count. Side Effects The major clinical toxicity of ...
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7.  Newly Approved Drug Therapies (310) Combivir, GlaxoSmithKline,
...most widely used antiretroviral medications for AIDS and HIV infection. Combivir, a combination of Retrovir (zidovudine or AZT) and Epivir (lamivudine or 3TC), could decrease the number of pills people with ...
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8.  News: Pfizer HIV Treatment Sees Positive Results (Clinical Trials Today)
...daily) to efavirenz, standard of care, (600 mg once daily), both dosed in combination with zidovudine/lamivudine. In the full set analysis, the rates of virologic suppression were 70.6% and ...
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9.  Newly Approved Drug Therapies (130) Zithromax (azithromycin), Pfizer,
...used concomitantly with many medications commonly prescribed for subjects with advanced HIV infections, such as zidovudine, didanosine, or rifabutin, without dosage adjustments. Currently, no data are available evaluating the concomitant use ...
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10.  CenterWatch: New Medical Therapies in Disease Category (179), HIV Infections
...daily) to efavirenz, standard of care, (600 mg once daily), both dosed in combination with zidovudine/lamivudine. In the full set analysis, the rates of virologic suppression were 70.6% and ...
...drugs to Sustiva produced significantly superior efficacy, vs. the addition of Combivir (lamivudine 150 mg/zidovudine 300 mg). Specifically, a significantly greater portion of subjects on Viread/Emtriva achieved HIV RNA ...
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11.  CenterWatch: New Medical Therapies in Disease Category (372), Vaccines
...daily) to efavirenz, standard of care, (600 mg once daily), both dosed in combination with zidovudine/lamivudine. In the full set analysis, the rates of virologic suppression were 70.6% and ...
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12.  CenterWatch: New Medical Therapies in Disease Category (182), Influenza
...daily) to efavirenz, standard of care, (600 mg once daily), both dosed in combination with zidovudine/lamivudine. In the full set analysis, the rates of virologic suppression were 70.6% and ...
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13.  CenterWatch: New Medical Therapies in Disease Category (2), AIDS and AIDS related infections
...daily) to efavirenz, standard of care, (600 mg once daily), both dosed in combination with zidovudine/lamivudine. In the full set analysis, the rates of virologic suppression were 70.6% and ...
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14.  Newly Approved Drug Therapies (256) Rescriptor Tablets (delavirdine mesylate tablets), Pharmacia & Upjohn,
...trials that began in April of 1994. Patients treated with the combination of Rescriptor plus zidovudine (AZT) showed a significantly greater reduction in the amount of virus in the blood for ...
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15.  Newly Approved Drug Therapies (63) Norvir (ritonavir), Abbott Laboratories,
...30, 1996. Norvir was given alone for the first 12 weeks, then in combination with zidovudine and /or didanosine. Side Effects The most common adverse effects were nausea (23% to 26% ...
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16.  Newly Approved Drug Therapies (844) Lexiva (fosamprenavir calcium), GlaxoSmithKline,
...Kost RG et al. Open-label phase II trial of amprenavir, abacavir, and fixed-dose zidovudine/lamivudine in newly and chronically HIV-1--infected patients. Journal of Acquired Immune Deficiency Syndromes ...
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17.  Newly Approved Drug Therapies (936) Tyzeka (telbivudine), Idenix Pharma,
...of telbivudine in cell culture with the HIV NRTIs abacavir, emtricitabine, lamivudine, tenofovir, zalcitibine, and zidovudine. Protocol Submission: February 2007 Final Report Submission: November 2007 • Idenix has agreed to conduct and ...
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18.  CenterWatch: Immunology/Infectious Diseases Approved Drug Therapies
...Pharmaceuticals; For the treatment of vaginal yeast infections, Approved April 2000 Trizivir (abacavir sulfate; lamivudine; zidovudine AZT) Tablet ; GlaxoSmithKline; For the treatment of HIV-1 infection, Approved November 2000 Drugs Approved ...
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19.  CenterWatch: List of Newly Approved Drug Thearapies
...Pharmaceuticals; For the treatment of vaginal yeast infections, Approved April 2000 Trizivir (abacavir sulfate; lamivudine; zidovudine AZT) Tablet ; GlaxoSmithKline; For the treatment of HIV-1 infection, Approved November 2000 Musculoskeletal Activella ...
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