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1. Newly Approved Drug Therapies (389) Rythmol, Knoll Pharmaceutical, ...for prolongation of the time to recurrence of paroxysmal atrial fibrillation/flutter and paroxysmal supraventricular tachycardia associated with disabling symptoms. The drug has been marketed in the U.S. since 1990 ...View Page
2. CenterWatch: New Medical Therapies in Disease Category (812), Myocardial Ischemia ...that the subjects receiving Ranexa had a 37% reduction in their relative risk of ventricular tachycardia lasting eight beats or more (p<0.001). In addition, there were fewer episodes of ...View Page
3. Newly Approved Drug Therapies (346) Neumega, Genetics Institute, ...Side Effects The most common adverse effects associated with Neumega treatment included peripheral edema, dyspnea, tachycardia, and conjunctival redness. Jobson Medical Information • Privacy | • Glossary Copyright © 1995-2010 Jobson Medical Information LLC ...View Page
4. Newly Approved Drug Therapies (470) Marplan Tablets, Roche, ...effects include: headaches, palpitation, neck stiffness, nausea or vomiting, sweating (fevers or clammy skin), photophobia, tachycardia, bradycardia, constricting chest pain, dilated pupils, intracranial bleeding and increased blood pressure. Jobson Medical Information ...View Page
5. Newly Approved Drug Therapies (29) Corvert Injection (ibutilide fumarate injection), Pharmacia & Upjohn, ...Effects A small number of subjects (1.7%) treated with Covert developed sustained polymorphic ventricular tachycardia (PVT), an arrhythmia of the ventricles. This side effect is common to antiarrhythmic agents used ...View Page
6. Newly Approved Drug Therapies (148) Risperdal Oral Formulation, Janssen Pharmaceutica, ...insomnia, agitation, EPS, headache, anxiety and rhinitis; less common were somnolence, dizziness, constipation, nausea, and tachycardia. Risperdal may also cause orthostatic hypotension, a form of low blood pressure, especially during the ...View Page
7. Study Posting (1918) Trial #159917, Kidney Cancer, Savannah, GA ...grade 2 • No ongoing atrial fibrillation • No history of serious ventricular arrhythmia (i.e., ventricular tachycardia or ventricular fibrillation ≥ 3 beats in a row) • QTc interval < 500 msec by baseline EKG ...View Page
8. CenterWatch Clinical Research Profile (1556) Trial #803, Wetlin Research Associates, Inc., San Diego, CA ...the other physicians listed below handle these disorders primarily for these clinical trial studies. Hypertension, Tachycardia, Arrhythmias, Diabetes (Type II), Hypothyroidism, Osteoarthritis, Rheumatoid arthritis, Chronic Pain, Osteoporosis, Orthopedics, Hyperthyroidism, End-Stage ...View Page
9. CenterWatch: New Medical Therapies in Disease Category (50), Coronary Artery Disease ...that the subjects receiving Ranexa had a 37% reduction in their relative risk of ventricular tachycardia lasting eight beats or more (p<0.001). In addition, there were fewer episodes of ...View Page
10. Newly Approved Drug Therapies (585) Synercid I.V., Rhone Poulenc Rorer, ...neck rigidity, neuropathy, pancytopenia, paraplegia, pericardial effusion, pericarditis, respiratory distress syndrome, shock, skin ulcer, supraventricular tachycardia, syncope, tremor, ventricular extrasystoles and ventricular fibrillation. Cases of hypotension and gastrointestinal hemorrhage were reported ...View Page
11. Newly Approved Drug Therapies (600) Evoxac, SnowBrand Pharmaceuticals, ...following: • Headache • Visual disturbance • Lacrimation • Sweating • Respiratory distress • Gastrointestinal spasm • Nausea • Vomiting • Diarrhea • Atrioventricular block • Tachycardia • Bradycardia • Hypotension • Hypertension • Shock • Mental confusion • Cardiac arrhythmia • Tremors Since the active ingredient, cevimeline, may ...View Page
12. Newly Approved Drug Therapies (602) Betapace AF Tablet, Berlex Laboratories, ...drug should be monitored carefully with electrocardiogram. Side effects may include: • Bradycardia • Fatigue • Fainting • Dizziness • Tachycardia • Severe diarrhea • Unusual sweating • Vomiting • Decreased appetite • Increased thirst Contraindications to Betapace AF include: • chronic ...View Page
13. Newly Approved Drug Therapies (715) Natrecor (nesiritide), Scios, ...Natrecor infusion in clinical trials include (but are not limited to) the following: • Hypotension • Ventricular tachycardia (abnormally fast heart rate) • Angina pectoris (chest pain) • Bradycardia (abnormally slow heart rate) • Headache • Abdominal ...View Page
14. Newly Approved Drug Therapies (788) Geodon (ziprasidone mesylate), Pfizer, ...because it is associated with torsade de pointes-type arrhythmia, a potentially fatal polymorphic ventricular tachycardia (rapid heart rate), and sudden death. In clinical studies, adverse events associated with the use ...View Page
15. Newly Approved Drug Therapies (875) Clolar (clofarabine), Genzyme, ...Febrile neutropenia • Systemic Inflammatory Response Syndrome (SIRS) • Vomiting • Nausea • Diarrhea • Pyrexia • Rigors • Abdominal Pain • Fatigue • Tachycardia • Anorexia Additionally, animal models have demostrated teratogenic potential in pregnant women. Human embryo toxicity has ...View Page
16. Newly Approved Drug Therapies (940) Invega (paliperidone), Janssen Pharmaceutica, ...use of Invega may include, but are not limited to, the following: • Parkinsonism • Akathisia • Dyskinesia • Tachycardia • Headache • Somnolence • Anxiety • Hyperkinesia • Extrapyramidal disorder • Dystonia In addition, Invega was shown to induce orthostatic ...View Page
17. Newly Approved Drug Therapies (624) Argatroban Injection, Texas Biotechnology Corporation, SmithKline Beecham, ...Side Effects Side effects may include: • Dyspnea • Hypotension • Fever • Diarrhea • Sepsis • Cardiac Arrest • Nausea • Ventricular tachycardia • Pain • Urinary tract infection • Vomiting • Infection • Pneumonia • Atrial fibrillation • Coughing • Abnormal renal function • Abdominal pain ...View Page
18. Clinical Trial Results by Drug Names ...In regard to cardiac adverse events, 1 patient in the Herceptin monotherapy arm developed supraventricular tachycardia and 2 patients in the combination arm had an episode of atrial fibrillation while on ...View Page
19. Study Posting (4878) Trial #118807, Osteoarthritis, Dallas, TX ...electrophysiologic instability including uncontrolled complex ventricular arrhythmia, uncontrolled atrial fibrillation or flutter, or uncontrolled supraventricular tachycardias within 3 months prior to randomization. The presence of an implantable defibrillator is not a ...View Page
20. Study Posting (2829) Trial #155112, Depression, San Antonio, TX ...medical condition which could be exacerbated by noradrenergic agents including unstable hypertension, unstable heart disease, tachycardia or tachyarrhythmia, narrow angle glaucoma, or urinary hesitation or retention • Have a history of severe ...View Page
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