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1. Study Posting (1570) Trial #156480, Coronary Artery Disease, Morristown, NJ ...NJ Trial Information IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (Study P04103AM3) A Multicenter, Double-Blind, Randomized Study to Establish the Clinical Benefit and Safety ...View Page
2. Study Posting (2040) Trial #95988, Coronary Artery Disease, Fort Lauderdale, FL ...Lauderdale, FL Trial Information Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting with Acute Coronary Syndrome. The intent of this clinical ...View Page
3. CenterWatch: New Medical Therapies in Disease Category (48), Congenital Heart Disease ...randomized, double-blind, active comparator trial, dubbed ENHANCE (Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous Familial Hypercholesterolemia), enrolled seven hundred and ...View Page
4. Study Posting (4519) Trial #112017, Diabetes Mellitus, Type 2, Tacoma, WA ...2, Tacoma, WA Trial Information A Drug-Drug Interaction Study of GK Activator (2) and Simvastatin in Patients With Type 2 Diabetes. Status: Completed Protocol Number: NP20413 Sponsor: Hoffman-La Roche ......randomized, open-label crossover study to investigate the potential interaction between GK Activator (2) and simvastatin in patients with type 2 diabetes Brief Summary: This study will assess the potential pharmacokinetic ...View Page
5. Study Posting (4519) Trial #111467, Diabetes Mellitus, Type 2, San Antonio, TX ...San Antonio, TX Trial Information A Drug-Drug Interaction Study of GK Activator (2) and Simvastatin in Patients With Type 2 Diabetes. Status: Completed Protocol Number: NP20413 Sponsor: Hoffman-La Roche ......randomized, open-label crossover study to investigate the potential interaction between GK Activator (2) and simvastatin in patients with type 2 diabetes Brief Summary: This study will assess the potential pharmacokinetic ...View Page
6. Study Posting (4519) Trial #98528, Rheumatoid Arthritis, Austin, TX ...98528, Rheumatoid Arthritis, Austin, TX Trial Information A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Status: Completed Protocol Number: WP18663 Sponsor: Hoffman-La Roche Company ......Division: Pharmaceutical Official Scientific Title: A randomized, open-label study to assess the pharmacokinetics of simvastatin and methotrexate in combination with tocilizumab in patients with rheumatoid arthritis. Brief Summary: This 2 ...View Page
7. Study Posting (4519) Trial #102958, Rheumatoid Arthritis, Duncansville, PA ...102958, Rheumatoid Arthritis, Duncansville, PA Trial Information A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Status: Completed Protocol Number: WP18663 Sponsor: Hoffman-La Roche Company ......Division: Pharmaceutical Official Scientific Title: A randomized, open-label study to assess the pharmacokinetics of simvastatin and methotrexate in combination with tocilizumab in patients with rheumatoid arthritis. Brief Summary: This 2 ...View Page
8. Study Posting (4519) Trial #101228, Rheumatoid Arthritis, Scottsdale, AZ ...101228, Rheumatoid Arthritis, Scottsdale, AZ Trial Information A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Status: Completed Protocol Number: WP18663 Sponsor: Hoffman-La Roche Company ......Division: Pharmaceutical Official Scientific Title: A randomized, open-label study to assess the pharmacokinetics of simvastatin and methotrexate in combination with tocilizumab in patients with rheumatoid arthritis. Brief Summary: This 2 ...View Page
9. Study Posting (4519) Trial #147618, Rheumatoid Arthritis, Christchurch, New Zealand ...Rheumatoid Arthritis, Christchurch, New Zealand Trial Information A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Status: Completed Protocol Number: WP18663 Sponsor: Hoffman-La Roche Company ......Division: Pharmaceutical Official Scientific Title: A randomized, open-label study to assess the pharmacokinetics of simvastatin and methotrexate in combination with tocilizumab in patients with rheumatoid arthritis. Brief Summary: This 2 ...View Page
10. Study Posting (4519) Trial #99422, Rheumatoid Arthritis, Oklahoma City, OK ...Rheumatoid Arthritis, Oklahoma City, OK Trial Information A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Status: Completed Protocol Number: WP18663 Sponsor: Hoffman-La Roche Company ......Division: Pharmaceutical Official Scientific Title: A randomized, open-label study to assess the pharmacokinetics of simvastatin and methotrexate in combination with tocilizumab in patients with rheumatoid arthritis. Brief Summary: This 2 ...View Page
11. Study Posting (4519) Trial #147886, Rheumatoid Arthritis, Royal Oak, MI ...Rheumatoid Arthritis, Royal Oak, MI Trial Information A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Status: Completed Protocol Number: WP18663 Sponsor: Hoffman-La Roche Company ......Division: Pharmaceutical Official Scientific Title: A randomized, open-label study to assess the pharmacokinetics of simvastatin and methotrexate in combination with tocilizumab in patients with rheumatoid arthritis. Brief Summary: This 2 ...View Page
12. Study Posting (172) Trial #88714, Dyslipidemia, San Antonio, TX ...study is to evaluate and compare the effects of once daily fenofibric acid monotherapy and simvastatin monotherapy with fenofibric acid and simvastatin combination therapy on CHD lipid risk factors in a population of patients with mixed dyslipidemia ...View Page
13. Study Posting (709) Trial #68794, Pulmonary Arterial Hypertension, Stanford, CA ...Posting (709) Trial #68794, Pulmonary Arterial Hypertension, Stanford, CA Trial Information Randomized trial of Zocor (simvastatin) in patients with Pulmonary Hypertension This study lasts 3 months and all patients receive study ......FDA, pharmaceutical, Pulmonary Arterial Hypertension description: CenterWatch Clinical Research Trial Posting: Randomized trial of Zocor (simvastatin) in patients with Pulmonary Hypertension ...View Page
14. Clinical Trial Results by Drug Names ...Clinical Trial Result Information Title of Study: A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. Fast Facts: Protocol number: WP18663 Sponsor: Hoffmann-La Roche Company ...View Page
15. Clinical Trial Results by Drug Names ...Result Information Title of Study: A Drug-Drug Interaction Study of GK Activator (2) and Simvastatin in Patients With Type 2 Diabetes. Fast Facts: Protocol number: NP20413 Sponsor: Hoffmann-La Roche ...View Page
16. CenterWatch: New Medical Therapies in Disease Category (170), High Cholesterol (Hyperlipidemia) ...randomized, double-blind, active comparator trial, dubbed ENHANCE (Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous Familial Hypercholesterolemia), enrolled seven hundred and ...View Page
17. Study Posting (748) Trial #150206, High Cholesterol (Hyperlipidemia), Harrisburg, NC ...Adequately Controlled with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg The purpose of this ......Adequately Controlled with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg High Cholesterol (Hyperlipidemia) Harrisburg ...View Page
18. Study Posting (577) Trial #127145, High Cholesterol (Hyperlipidemia), Richmond, VA ...high cholesterol and have been taking a statin drug such as Lipitor, Zocor, Crestor or Simvastatin for at least 3 months, you may qualify for a clinical trial. For more information ...View Page
19. Study Posting (709) Trial #50652, Alzheimer's Disease, Palo Alto, CA ...disease (CLASP study) CLASP is a research study to investigate the safety and effectiveness of simvastatin (a cholesterol lowering drug or statin) to slow the progression of Alzheimer’s disease (AD ...View Page
20. Newly Approved Drug Therapies (333) Zocor, Merck, ...Company: Merck Approval Status: Approved November 1997 Treatment Area: high triglyceride levels General Information Zocor (simvastatin) has been approved as a treatment for lowering triglyceride levels in addition to its established ...View Page
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