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1.  CenterWatch: New Medical Therapies in Disease Category (405), Common Cold
...dosing. Consistent trends were demonstrated with other symptoms as compared to placebo, including improvements in rhinorrhea (runny nose), nasal congestion, cough, facial pain and pressure and sleep disturbance. INS37217 was well ...
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2.  Newly Approved Drug Therapies (952) Xyzal (levocetirizine dihydrochloride), UCB,
...Efficacy was assessed using a total symptom score from patient recording of 4 symptoms (sneezing, rhinorrhea, nasal pruritus, and ocular pruritus) in five studies and 5 symptoms (sneezing, rhinorrhea, nasal pruritus, ocular pruritus, and nasal congestion) in one study. Symptoms were recorded using a ...
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3. Clinical Trial Results by Drug Names
...4 patients out of 68 experienced adverse events (peripheral oedema, central line infection, vasovagal syncope, rhinorrhea). Two of these patients had adverse events attributed to pertuzumab and compatible with infusion-associated symptoms (vasovagal syncope, rhinorrhea). Overall, there was no clear evidence of a dose relationship. Conclusions: None of the patients ...
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4.  Newly Approved Drug Therapies (982) Patanase (olopatadine hydrochloride), Alcon,
...two weeks. Efficacy was based on patient recording of 4 individual nasal symptoms (nasal congestion, rhinorrhea, itchy nose, and sneezing) on a 0 to 3 categorical severity scale (0 = absent, 3 ...
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5.  CenterWatch: New Medical Therapies in Disease Category (166), Allergy
...prostaglandin D2 (PGD2), a key immune mediator correlated with improvements in the allergic symptoms of rhinorrhea. The single dose, randomized, double blind, crossover trial enrolled 20 subjects. Subjects received one dose ...
...to subjects on placebo. The total nasal symptom score was a composite of four symptoms: rhinorrhea, nasal congestion, nasal itching and post-nasal drip. The randomized, double blind, placebo-controlled study ...
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6.  Newly Approved Drug Therapies (949) Veramyst (fluticasone furoate), GlaxoSmithKline,
...was calculated as the sum of the patients’ scoring of the 4 individual nasal symptoms (rhinorrhea, nasal congestion, sneezing, and nasal itching) on a 0 to 3 categorical severity scale (0 ...
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7.  Newly Approved Drug Therapies (861) Apokyn (apomorphine hydrochloride), Mylan Bertek Pharmaceuticals,
...include (but are not limited to) the following: • Yawning • Dyskinesias • Drowsiness/Somnolence • Dizziness/Postural Hypotension • Rhinorrhea • Hallucinations • Edema/Inflammation In addition, Apokyn has been associated with a very high incidence on ...
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8. Clinical Trial Results by Drug Names
...5 patients, 36%) were pyrexia, headache, vomiting, cough, upper abdominal pain, decreased appetite, dermatitis, and rhinorrhea. The majority of adverse events were mild in intensity. No serious adverse events occurred. Three ...
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9.  Newly Approved Drug Therapies (972) Kuvan (sapropterin dihydrochloride), BioMarin Pharmaceuticals,
...Kuvan may include, but are not limited to, the following: • Headache • Upper respiratory tract infection • Rhinorrhea • Pharyngolaryngeal pain • Diarrhea • Vomiting • Cough • Pyrexia Mechanism of Action Kuvan (sapropterin dihydrochloride) is a synthetic ...
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