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1.  CenterWatch: New Medical Therapies in Disease Category (608), Pseudobulbar Affect
...August 17, 2009 Avanir released positive results from a phase III trial of Zenvia (dextromethorphan/quinidine) for the treatment of pseudobulbar affect (PBA). This double-blind, randomized, placebo-controlled, international study ...
...Pharmaceuticals reported positive results of its first phase III trial of their drug Neurodex (dextromethorphan/quinidine) , for the treatment of pseudobulbar affect in patients with amyotrophic lateral sclerosis. Trial data indicated ...
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2.  Study Posting (77) Trial #138520, Neurologic Disorders, New York, NY
...and schizophrenia) • Have active epilepsy • Have liver or kidney failure • Have been treated with quinine, quinidine, chloroquine, or halofantrine • Are pregnant, breastfeeding, or intend to become pregnant during the study • Have ...
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3.  CenterWatch: New Medical Therapies in Disease Category (253), Diabetic Neuropathy
...23, 2007 Avanir announced positive results from a phase III trial of Zenvia (dextromethorphan hydrobromide/quinidine sulfate, "DMQ") for the treatment of diabetic neuropathic pain. This randomized, double-blind, placebo-controlled ...
...Israel. Subjects were placed into one of three treatment arms: 45 mg dextromethorphan /30 mg quinidine (DMQ 45) BID dose, 30 mg dextromethorphan / 30 mg quinidine BID dose (DMQ 30) and ...
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4.  Study Posting (1918) Trial #160135, Metastatic Cancer, Savannah, GA
...Select anesthetics (e.g., ketamine, propofol) • Hypericum perforatum (St. John's wort) • Nefazodone • Nicardipine • Diclofenac • Quinidine • Imatinib mesylate • At least 7 days since prior and no concurrent medications that prolong the QTc interval, including any of the following: • Antiarrhythmic agents (e.g., quinidine, procainamide, disopyramide phosphate, amiodarone, sotalol hydrochloride, ibutilide, dofetilide) • Antipsychotic agents (e.g., chlorpromazine, mesoridazine, thioridazine ...
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5.  Study Posting (1918) Trial #160134, Breast Cancer, Savannah, GA
...Select anesthetics (e.g., ketamine, propofol) • Hypericum perforatum (St. John's wort) • Nefazodone • Nicardipine • Diclofenac • Quinidine • Imatinib mesylate • At least 7 days since prior and no concurrent medications that prolong the QTc interval, including any of the following: • Antiarrhythmic agents (e.g., quinidine, procainamide, disopyramide phosphate, amiodarone, sotalol hydrochloride, ibutilide, dofetilide) • Antipsychotic agents (e.g., chlorpromazine, mesoridazine, thioridazine ...
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6.  CenterWatch: New Medical Therapies in Disease Category (215), Neuropathy
...Pharmaceuticals reported positive results of its first phase III trial of their drug Neurodex (dextromethorphan/quinidine) , for the treatment of pseudobulbar affect in patients with amyotrophic lateral sclerosis. Trial data indicated ...
...drugs (3.3 points greater vs. dextromethorphan, p=0.001; 3.7 points greater vs. quinidine, p<0.001). The drug also met all secondary endpoints, including reduction in affect episode ...
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7.  CenterWatch: New Medical Therapies in Disease Category (160), Amyotrophic Lateral Sclerosis (ALS)
...Pharmaceuticals reported positive results of its first phase III trial of their drug Neurodex (dextromethorphan/quinidine) , for the treatment of pseudobulbar affect in patients with amyotrophic lateral sclerosis. Trial data indicated ...
...drugs (3.3 points greater vs. dextromethorphan, p=0.001; 3.7 points greater vs. quinidine, p<0.001). The drug also met all secondary endpoints, including reduction in affect episode ...
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8.  CenterWatch: New Medical Therapies in Disease Category (107), Obesity
...23, 2007 Avanir announced positive results from a phase III trial of Zenvia (dextromethorphan hydrobromide/quinidine sulfate, "DMQ") for the treatment of diabetic neuropathic pain. This randomized, double-blind, placebo-controlled ...
...Israel. Subjects were placed into one of three treatment arms: 45 mg dextromethorphan /30 mg quinidine (DMQ 45) BID dose, 30 mg dextromethorphan / 30 mg quinidine BID dose (DMQ 30) and ...
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9.  Study Posting (1918) Trial #158907, Lung Cancer, Savannah, GA
...s wort) • Efavirenz • Tipranavir • No concurrent agents with proarrhythmic potential, including any of the following: • Quinidine • Procainamide • Disopyramide • Sotalol • Probucol • Haloperidol • Risperidone • Indapamide • Flecainide • No concurrent therapeutic anticoagulation for thromboembolic disease ...
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10.  Study Posting (1918) Trial #159917, Kidney Cancer, Savannah, GA
...or phenobarbital) • Hypericum perforatum (St. John's wort) • Ketoconazole • Dexamethasone • Dysrhythmic drugs (i.e., terfenadine, quinidine, procainamide, sotalol, probucol, bepridil, indapamide, or flecainide) • Haloperidol • Risperidone • Rifampin • Grapefruit juice or grapefruit NOTE ...
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11.  Study Posting (1918) Trial #158881, Brain Tumor, Savannah, GA
...cancer allowed • Concurrent hormonal therapy for breast or prostate cancer allowed • No concurrent bethanechol, ketoconazole, quinidine, or succinylcholine • No prior GliaSite or other type of brain brachytherapy, convection enhanced delivery of ...
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12.  Newly Approved Drug Therapies (64) Crixivan (Indinavir sulfate), Merck,
...and zidovudine, d4T, lamivudine, fluconazole, clarithromycin, trimethoprim/sulfamethoxazole, isoniazid, Ortho-Novum 1/35, cimetidine, and quinidine. Jobson Medical Information • Privacy | • Glossary Copyright © 1995-2010 Jobson Medical Information LLC. Designed by Piehead ...
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