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1.  Study Posting (3684) Trial #155654, Constipation, Edina, MN
...Study Posting (3684) Trial #155654, Constipation, Edina, MN Trial Information Opioid Induced Constipation Study Opioid Induced Constipation You may be eligible to participate if you: • Have had non-cancer pain ...
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2.  Study Posting (333) Trial #155685, Constipation, Bingham Farms, MI
...Study Posting (333) Trial #155685, Constipation, Bingham Farms, MI Trial Information Treatment for Constipation from Opioid Use Long-term opioid use can cause constipation. This reasearch study is recruiting paitents who are taking opioids for ...
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3.  Study Posting (5184) Trial #156468, Pain, Chicago, IL
...Pain, Chicago, IL Trial Information Adults age 18 or older with nonmalignant pain who have opioid induced constipation. A multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the safety, efficacy, and tolerability of subcutaneous MOA-728 versus placebo in subjects who have opioid induced constipation. At screening • Male and female subjects aged 18 years or older. • Subjects weighing ...
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4.  Study Posting (1843) Trial #140886, Bowel Dysfunction, Baton Rouge, LA
...Study Posting (1843) Trial #140886, Bowel Dysfunction, Baton Rouge, LA Trial Information Opioid-induced Bowel Dysfunction A 12 week study for adults 18 and older with bowel dysfunction caused by more than 90 days of pain medication (opioid) use. Patient Inclusion Criteria Adults 18 or older with Bowel Dysfunction caused by or made ...
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5.  Study Posting (557) Trial #118480, Constipation, Tampa, FL
...Study Posting (557) Trial #118480, Constipation, Tampa, FL Trial Information Opioid Induced Constipation Bringing Your Life To A Standstill? Get Moving and Join our OIC Research ...
...injected daily, when compared to placebo (inactive substance), for constipation caused by the pain medicine (opioids) usually prescribed for men and women with chronic, non-cancer related pain. You may be ...
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6.  CenterWatch: New Medical Therapies in Disease Category (219), Addictions
...reported positive results from a phase III trial of XR-NTX for the treatment of opioid dependence. This randomized, multi-center study enrolled 250 subjects who were dependent on opioids and who had recently been detoxified and abstinent from opioids for a minimum of seven ...
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7.  Newly Approved Drug Therapies (1038) Onsolis (fentanyl buccal), BioDelivery Sciences,
...Area: breakthrough cancer pain General Information Onsolis is an oral transmucosal form of the potent opioid analgesic, fentanyl citrate, a pure opioid agonist whose principal therapeutic action is analgesia. The precise mechanism of the analgesic action is ...
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8.  Study Posting (24) Trial #127471, Bowel Dysfunction, Henderson, NV
...Placebo-controlled, Double-blinded Study of the Efficacy and Safety of Lubiprostone in Patients with Opioid-induced Bowel Dysfunction This is a study to assess the efficacy and safety of oral lubiprostone for Opioid-Induced Bowel Dysfunction. Patient Inclusion Criteria • At least 18 years of age • Have been treated ...
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9.  Study Posting (5204) Trial #149628, Constipation, Winter Park, FL
...Trial #149628, Constipation, Winter Park, FL Trial Information A clinical trial for the treatment of Opioid Induced Chronic Constipation in the Chronic Pain Patient Do you have constipation from the pain ...
...are taking? You may qualify for a 52 week clinical trial for the treatment of Opioid Induced Chronic Constipation. It is a subcutaneous injection, (given just under the skin) self administered ...
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10.  Study Posting (799) Trial #162609, Pain, Boston, MA
...Study Posting (799) Trial #162609, Pain, Boston, MA Trial Information Opioid treatment for Chronic Low Back Pain (CLBP) and the Impact of Mood Symptoms The Pain ...
...problems with lumbar discs for a research study. This study is on the effectiveness of opioid medication (morphine) for chronic low back pain. You must have an MRI confirmation of you ...
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11.  Newly Approved Drug Therapies (987) Entereg (alvimopan), GlaxoSmithKline,
...May 2008 Treatment Area: postoperative ileus General Information Entereg is an oral, peripherally-acting, mu-opioid receptor (PAMOR) antagonist. Following oral administration, alvimopan antagonizes the peripheral effects of opioids on gastrointestinal motility and secretion by competitively binding to gastrointestinal tract mu-opioid receptors. Entereg ...
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12.  Study Posting (799) Trial #162599, Lower Back Pain, Boston, MA
...Study Posting (799) Trial #162599, Lower Back Pain, Boston, MA Trial Information Opioid treatment for Chronic Low Back Pain (CLBP) and the Impact of Mood Symptoms The Pain ...
...problems with lumbar discs for a research study. This study is on the effectiveness of opioid medication (morphine) for chronic low back pain. You must have an MRI confirmation of you ...
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13.  Study Posting (799) Trial #156603, Constipation, Boston, MA
...Label Study to Evaluate the Long-term Safety of Subcutaneous MOA-728 for Treatment of Opioid-Induced Constipation in Subjects with Non-Malignant Pain Are you suffering from Chronic Constipation from using opioid medications? If so you may be eligible for a clinical research study at Brigham and ...
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14.  Study Posting (799) Trial #156612, *Healthy Patient Studies, Boston, MA
...Label Study to Evaluate the Long-term Safety of Subcutaneous MOA-728 for Treatment of Opioid-Induced Constipation in Subjects with Non-Malignant Pain Are you suffering from Chronic Constipation from using opioid medications? If so you may be eligible for a clinical research study at Brigham and ...
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15.  Newly Approved Drug Therapies (1044) Embeda (morphine sulfate and naltrexone hydrochloride), King Pharmaceuticals,
...hydrochloride. Morphine sulfate is an agonist and naltrexone hydrochloride is an antagonist at the mu-opioid receptor. Morphine provides analgesic and sedative effects while naltrexone hydrochloride reverses the subjective and analgesic ...
...indicated for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. Embeda is supplied as a capsule ...
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16.  Study Posting (1360) Trial #150696, Addictions, Lexington, KY
...Information Drugs & Dependencies: Volunteers Needed for Research Study on Opiate Use • Do you currently use opioid drugs like Lortab®, Percocet®, or heroin recreationally (for non-medical reasons)? • Have you ever injected opioid drugs? If so, and you are interested in participating in a research study, please call ...
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17.  Study Posting (2829) Trial #155116, Constipation, San Antonio, TX
...Antonio, TX Trial Information Study Evaluating Long-Term Safety of MOA-728 in Subjects With Opioid-Induced Constipation This is a one-year study to evaluate the long-term safety and ...
...the subcutaneous (just under the skin) injection form of MOA-728 for the treatment of opioid-induced constipation in subjects with nonmalignant pain. The study consists of a 2 week screening ...
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18.  CenterWatch: New Medical Therapies in Disease Category (45), Chronic Pain
...of chronic pain. This US-based, randomized withdrawal, placebo-controlled, double-blind trial enrolled 268 opioid-tolerant subjects with chronic moderate to severe low back pain. The subjects received placebo or ...
...safety profile and reported adverse events in the study were consistent with that of other opioids. March 23, 2009 Durect reported positive results from a phase IIb trial of Transdur-sufentanil ...
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19.  Study Posting (799) Trial #160048, Chronic Pain, Boston, MA
...Trial #160048, Chronic Pain, Boston, MA Trial Information Pain Responses in Patients on Long-Term Opioid Therapy for Chronic Pain Chronic Pain Research Study The Massachusetts General Hospital Center for Translational ...
...with chronic pain for a research study. The study is looking at the effect of opioid (narcotic) pain medicines on pain sensation, threshold and tolerance. The study consists of one visit ...
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20.  Study Posting (799) Trial #159997, Chronic Pain, Boston, MA
...Trial #159997, Chronic Pain, Boston, MA Trial Information Pain Responses in Patients on Long-Term Opioid Therapy for Chronic Pain Chronic Pain Research Study The Massachusetts General Hospital Center for Translational ...
...with chronic pain for a research study. The study is looking at the effect of opioid (narcotic) pain medicines on pain sensation, threshold and tolerance. The study consists of one visit ...
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