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1. Newly Approved Drug Therapies (64) Crixivan (Indinavir sulfate), Merck, ...Newly Approved Drug Therapies (64) Crixivan (Indinavir sulfate), Merck, Drug Information The following information is obtained from various newswires, published medical journal articles, and medical conference presentations. Drug Name: Crixivan (Indinavir sulfate) Company: Merck Approval Status: Approved March 1996 Treatment Area: HIV infection General Information Crixivan ...View Page
2. Study Posting (2380) Trial #157521, Erectile Dysfunction, Lawrenceville, NJ ...drug abuse • hypoactive sexual desire • premature ejaculation • Con meds: • Erythromycin • Intraconazole, ketoconazole • Ritonavir, saquinavir, amprenavir, indinavir, nelfinavir • Cimetidine • Anticoagulants • Trazodone AdvanceMed Research 2 Princess Rd., Suite J Lawrenceville, NJ 8648 Phone ...View Page
3. Study Posting (1918) Trial #160135, Metastatic Cancer, Savannah, GA ...CYP3A4 inhibitors, including any of the following: • HIV protease inhibitors (e.g., amprenavir, atazanavir, fosamprenavir, indinavir, nelfinavir, ritonavir) • Select antibiotics (e.g., ciprofloxacin, clarithromycin, doxycycline, enoxacin, isoniazid, telithromycin) • Azole antifungals (e ...View Page
4. Study Posting (1918) Trial #158907, Lung Cancer, Savannah, GA ...of the following: • Azole antifungals (ketoconazole, itraconazole) • Diltiazem • Clarithromycin • Erythromycin • Verapamil • Delavirdine • HIV protease inhibitors (indinavir, saquinavir, ritonavir, atazanavir, nelfinavir) • More than 12 days since prior and no concurrent CYP3A4 inducers ...View Page
5. Study Posting (1918) Trial #159848, Lung Cancer, Savannah, GA ...antifungals (e.g., ketoconazole, itraconazole) • Diltiazem • Clarithromycin • Erythromycin • Verapamil • Delavirdine • HIV protease inhibitors (e.g., indinavir, saquinavir, ritonavir, atazanavir, nelfinavir) • At least 12 days since prior and no concurrent CYP3A4 inducers ...View Page
6. Study Posting (1918) Trial #160134, Breast Cancer, Savannah, GA ...CYP3A4 inhibitors, including any of the following: • HIV protease inhibitors (e.g., amprenavir, atazanavir, fosamprenavir, indinavir, nelfinavir, ritonavir) • Select antibiotics (e.g., ciprofloxacin, clarithromycin, doxycycline, enoxacin, isoniazid, telithromycin) • Azole antifungals (e ...View Page
7. Newly Approved Drug Therapies (903) Sprycel (dasatinib), Bristol-Myers Squibb, ...which inhibit this enzyme (including but not limited to ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, atazanavir, indinavir, nefazodone, nelfinavir, saquinavir, telithromycin) may affect the pharmacokinetics of Sprycel and increase acute drug exposure ...View Page
8. Newly Approved Drug Therapies (988) Aptivus (tipranavir), Boehringer Ingelheim, ...optimal backgroumd therapy (OBR) or a ritonavir-boosted protease inhibitor (PI) (lopinavir, amprenavir, saquinavir or indinavir) plus OBR. The studies evaluated treatment response at 48 weeks. Through 48 weeks of treatment ...View Page
9. Newly Approved Drug Therapies (880) Aptivus (tipranavir), Boehringer Ingelheim, ...regimen (OBR), or a control regimen of an approved protease inhibitor (lopinavir, amprenavir, saquinavir or indinavir) in combination with ritonavir plus OBR for 24 weeks. Trial data indicated that Aptivus produced ...View Page
10. Newly Approved Drug Therapies (890) Vaprisol (conivaptan), Astellas, ...drugs that inhibit this enzyme (including but not limited to ketoconazole, itraconazole, clarithromycin, ritonavir, and indinavir) may increase serum Vaprisol concentration and halflife, and should be avoided. Second, clinical studies indicated ...View Page
11. CenterWatch: Immunology/Infectious Diseases Approved Drug Therapies ...Approved May 1996 Confide ; Johnson & Johnson; HIV testing and counseling service, Approved May 1996 Crixivan (Indinavir sulfate) ; Merck; Treatment for HIV infection, Approved March 1996 Gastrocrom Oral Concentrate (cromolyn sodium) ; Rhone ...View Page
12. CenterWatch: List of Newly Approved Drug Thearapies ...Approved May 1996 Confide ; Johnson & Johnson; HIV testing and counseling service, Approved May 1996 Crixivan (Indinavir sulfate) ; Merck; Treatment for HIV infection, Approved March 1996 Gastrocrom Oral Concentrate (cromolyn sodium) ; Rhone ...View Page
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