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1. CenterWatch: New Medical Therapies in Disease Category (695), Atopic Dermatitis ...dermatitis. This randomized, double-blind, active controlled trial enrolled seventeen subjects who received TF002 or hydrocortisone. The primary endpoint was the reduction of inflammation in atopic skin after three weeks, measured ......improvement in TIS (Three Item Severity) score. The endpoint was reached; both TF-002 and hydrocortisone improved three item severity scores by more than 1.5. At a four week follow ...View Page
2. Newly Approved Drug Therapies (168) Elliotts B Solution (buffered intrathecal electrolyte/dextrose injection), Orphan Medical, ...J.C., et al. "Evaluation of some pharmaceutical aspects of intrathecal methotrexate sodium, cytarabine, and hydrocortisone sodium succinate." American Journal of Hospital Pharmacy (1978); 35:402. Additional Information Acute lymphocytic leukemia ...View Page
3. Newly Approved Drug Therapies (907) Verdeso (desonide), Connetics Corporation, ...Multicenter trial for long-term safety and efficacy comparison of 0.05% desonide and 1% hydrocortisone ointments in the treatment of atopic dermatitis in pediatric patients. Journal of the American Academy ......Versailles J, Couzinier JP Comparison of the cutaneous/systemic antiinflammatory activity ratios for desonide and hydrocortisone in various experimental models. Arzneimittelforschung 1988 Apr;38(4):542-5. Additional Information For additional ...View Page
4. Study Posting (5267) Trial #147268, Solid Tumors, Houston, TX ...as radiation, antimetabolites, alkylators, antilymphocytic sera, systemic corticosteroids) within 1 month prior to enrollment. Topical hydrocortisone up to a concentration of <=1% will be allowed. • Patient has known acquired, inherited, or ...View Page
5. Study Posting (5267) Trial #147270, Solid Tumors, Philadelphia, PA ...as radiation, antimetabolites, alkylators, antilymphocytic sera, systemic corticosteroids) within 1 month prior to enrollment. Topical hydrocortisone up to a concentration of <=1% will be allowed. • Patient has known acquired, inherited, or ...View Page
6. Study Posting (5267) Trial #147269, Solid Tumors, Tampa, FL ...as radiation, antimetabolites, alkylators, antilymphocytic sera, systemic corticosteroids) within 1 month prior to enrollment. Topical hydrocortisone up to a concentration of <=1% will be allowed. • Patient has known acquired, inherited, or ...View Page
7. Study Posting (1918) Trial #158884, Prostate Cancer, Savannah, GA ...e.g., aminoglutethimide, diethylstilbestrol, or estramustine) allowed Prior steroid therapy (e.g., dexamethasone, prednisone, or hydrocortisone) allowed • Radiotherapy: At least 4 weeks since prior radiotherapy and recovered No prior strontium chloride ...View Page
8. Study Posting (1918) Trial #158883, Leukemia, Savannah, GA ...to administration of study drug • Prior steroid allowed as clinically indicated for patients with asthma • Hydrocortisone and methylprednisolone allowed as premedication in patients with a history of severe allergic reactions • At ...View Page
9. Newly Approved Drug Therapies (937) Desonate (desonide), Dow Pharm, ...Multicenter trial for long-term safety and efficacy comparison of 0.05% desonide and 1% hydrocortisone ointments in the treatment of atopic dermatitis in pediatric patients. Journal of the American Academy ...View Page
10. Study Posting (455) Trial #117567, Ulcerative Colitis, Wheat Ridge, CO ...TNF agent at an approved labeled dose for at least 8 weeks and/or • Intravenous hydrocortisone = 400 mg/day (or equivalent) for at least 1 week. • had been intolerant to one ...View Page
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