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1. CenterWatch: New Medical Therapies in Disease Category (243), Atrial Fibrillation ...fibrillation for more than 72 hours. The subjects received dronedarone (400 mg twice daily) or amiodarone (600mg loading dose daily for 28 days, then 200mg daily thereafter) over seven months. The ......73.9% of subjects in the dronedarone arm as compared to 55.3% in the amiodarone arm (p<0.001). Atrial fibrillation after electrical cardioversion occurred in 36.5% of subjects ...View Page
2. Newly Approved Drug Therapies (1036) Multaq (dronedarone), Sanofi-aventis, ...Vaughan-Williams classes. The exact mechanism of action is unknown. Dronedarone is a derivative of amiodarone, an effective yet toxic antiarrhythmic drug. Unlike amiodarone, dronedarone does not contain idodine atoms and hence contains the efficacy of amiodarone but without ...View Page
3. Study Posting (5170) Trial #138937, Atrial Fibrillation, Milwaukee, WI ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
4. Study Posting (5170) Trial #138936, Atrial Fibrillation, Elkhorn, WI ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
5. Study Posting (5170) Trial #138935, Atrial Fibrillation, Beloit, WI ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
6. Study Posting (5170) Trial #154910, Atrial Fibrillation, Springfield, VA ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
7. Study Posting (5170) Trial #154909, Atrial Fibrillation, Richlands, VA ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
8. Study Posting (5170) Trial #154908, Atrial Fibrillation, Galax, VA ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
9. Study Posting (5170) Trial #154907, Atrial Fibrillation, Chesapeake, VA ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
10. Study Posting (5170) Trial #154906, Atrial Fibrillation, Arlington, VA ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
11. Study Posting (5170) Trial #154905, Atrial Fibrillation, Salt Lake City, UT ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
12. Study Posting (5170) Trial #138934, Atrial Fibrillation, Waco, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
13. Study Posting (5170) Trial #154904, Atrial Fibrillation, Tyler, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
14. Study Posting (5170) Trial #138933, Atrial Fibrillation, Plano, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
15. Study Posting (5170) Trial #154903, Atrial Fibrillation, Orange, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
16. Study Posting (5170) Trial #138931, Atrial Fibrillation, Odessa, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
17. Study Posting (5170) Trial #138930, Atrial Fibrillation, McKinney, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
18. Study Posting (5170) Trial #154902, Atrial Fibrillation, Lubbock, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
19. Study Posting (5170) Trial #154901, Atrial Fibrillation, Humble, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
20. Study Posting (5170) Trial #154900, Atrial Fibrillation, Houston, TX ...Exclusion Criteria: • Permanent (chronic) atrial fibrillation • Antiarrhythmic drug therapy which cannot be stopped • Use of amiodarone with prior 12 months • History of unsuccessful cardioversion • History of stroke within prior 6 months ...View Page
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