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1.  Newly Approved Drug Therapies (978) Accretropin (somatropin rDNA Original), Cangene Corp,
...produced by recombinant DNA technology during fermentation in E. coli, yielding a protein containing 192 amino acids. The N-terminal amino acid, methionine, is later removed to yield a protein that is ...
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2.  Newly Approved Drug Therapies (866) Campral (acamprosate calcium), Forest Laboratories,
...2004 Treatment Area: Alcohol dependence General Information Campral (acamprosate) is a structural analogue of the amino acid homotaurine and the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). While it's specific mechanism of ...
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3.  Newly Approved Drug Therapies (1049) Zenpep (pancrelipase), Eurand,
...catalyze the hydrolysis of fats to monoglycerol, glycerol and fatty acids, protein into peptides and amino acids, and starch into dextrins and short chain sugars in the duodenum and proximal small intestine ...
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4.  Newly Approved Drug Therapies (1014) Atryn (antithrombin recombinant lyophilized powder for reconstitution), GTC BioTherapeutics,
...recombinant antithrombin. Recombinant antithrombin is produced by recombinant DNA technology using genetically engineered goats. The amino acid sequence of recombinant antithrombin is identical to that of human plasma-derived antithrombin. Antithrombin plays ...
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5.  Newly Approved Drug Therapies (765) Orfadin (nitisinone), Orphan Pharmaceuticals,
...1 is a genetic metabolic disorder that results from an inability to break down the amino acid tyrosine. Because of resulting liver failure and liver cancer, children with HT-1 rarely survive ...
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6.  Study Posting (469) Trial #162759, Autism, Shreveport, LA
...30 days of entering study: • Chelating Agents • Any enzyme product • Pancreatin, thyroid, or adrenal extract • Amino acids • Must not have cerebral palsy This is a Phase III multi-center, randomized, double-blind ...
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7.  Study Posting (799) Trial #163139, Amyotrophic Lateral Sclerosis (ALS), Boston, MA
...transgenic mouse model of ALS [1]. Preclinical evidence suggests that the extracellular accumulation of excitatory amino acids (EAAs) such as glutamate and the excessive activation of EAA receptors contribute to the neuronal ...
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8.  Study Posting (799) Trial #163131, Amyotrophic Lateral Sclerosis (ALS), Boston, MA
...transgenic mouse model of ALS [1]. Preclinical evidence suggests that the extracellular accumulation of excitatory amino acids (EAAs) such as glutamate and the excessive activation of EAA receptors contribute to the neuronal ...
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9.  Study Posting (799) Trial #156966, Amyotrophic Lateral Sclerosis (ALS), Boston, MA
...transgenic mouse model of ALS [1]. Preclinical evidence suggests that the extracellular accumulation of excitatory amino acids (EAAs) such as glutamate and the excessive activation of EAA receptors contribute to the neuronal ...
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10.  Study Posting (799) Trial #156976, *Healthy Patient Studies, Boston, MA
...transgenic mouse model of ALS [1]. Preclinical evidence suggests that the extracellular accumulation of excitatory amino acids (EAAs) such as glutamate and the excessive activation of EAA receptors contribute to the neuronal ...
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11.  Study Posting (709) Trial #44676, Peripheral Arterial Occlusive Disease, Stanford, CA
...safely treat your leg pain by improving blood flow. L-arginine is a substance (an amino acid) normally present in the body. In human studies it has been shown to restore blood ...
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12.  Study Posting (709) Trial #44677, Claudication, Stanford, CA
...safely treat your leg pain by improving blood flow. L-arginine is a substance (an amino acid) normally present in the body. In human studies it has been shown to restore blood ...
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13.  CenterWatch Clinical Industry Provider Profile(4157), SpectraCell Laboratories, Houston, TX
...measures how an individual's white blood cells respond to varied environments of vitamins, minerals, amino acids and antioxidants. By evaluating the functionality of specific nutrients in a patient's own cells ...
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14.  Newly Approved Drug Therapies (61) Humalog (insulin lispro), Eli Lilly,
...of insulin injected under the skin could be accelerated by changing the order of two amino acids in the human insulin molecule. Humalog is designed to more closely mimic the body's ...
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15.  Newly Approved Drug Therapies (589) Comtan, Novartis,
...plasma pharmokinetics of levodopa. When entacapone is given in conjunction with levodopa and an aromatic amino acid decarboxylase inhibitor, such as carbidopa, plasma levels of levodopa are greater and more sustained than ...
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16.  Newly Approved Drug Therapies (812) Forteo (teriparatide), Eli Lilly,
...1-34), [rhPTH(1-34)], which has an identical sequence to the 34 N-terminal amino acids (the biologically active region) of the 84-amino acid human parathyroid hormone. Studies have shown ...
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17.  Newly Approved Drug Therapies (834) Bexxar, Corixa,
...of mammalian cells and is composed of two murine gamma 2a heavy chains of 451 amino acids each and two lambda light chains of 220 amino acids each. Iodine 131 Tositumomab is ...
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18.  Newly Approved Drug Therapies (936) Tyzeka (telbivudine), Idenix Pharma,
...determine the susceptibility in cell culture of HBV harboring the following mutations of highly conserved amino acid residues among HBV isolates: R22C, W58G, L69P, L82M, P99L, L180M, L209V, T240I, I254F, P261L, G295E ...
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19.  CenterWatch: New Medical Therapies in Disease Category (499), Attention Deficit/Hyperactivity Disorder (ADHD - Adults)
...New River Pharmaceuticals has announced positive results of a phase III trial of NRP104 , their amino- acid-conjugated stimulant under investigation for the treatment of pediatric attention deficit hyperactivity disorder (ADHD). Trial ...
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20.  CenterWatch: New Medical Therapies in Disease Category (385), Blood Clots
...a second phase I study investigating ETC-642 ( RLT Peptide ), a complex of a 22-amino acid peptide and phospholipids for the treatment of cardiovascular disease. Results demonstrated the drug was safe ...
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