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1.  Study Posting (1387) Trial #118112, High Cholesterol (Hyperlipidemia), Gilbert, AZ
...research study to evaluate the effectiveness and safety of the study medication in combination with “statins” compared with “statins” alone for 12 weeks in subjects with hypercholesterolemia (high cholesterol). An optional 48-week extension ...
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2.  Study Posting (96) Trial #151318, Muscle Pain, New York, NY
...The Rockefeller University Hospital is conducting a study looking at the relationship between cholesterol-lowering statin medications and muscle pain. Volunteers who participate in the study will be randomly placed in a group that will receive statin treatment or a group that will receive a placebo – a pill that looks like the ...
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3.  Newly Approved Drug Therapies (1007) Trilipix (fenofibric acid), Abbott Laboratories,
...Trilipix as an adjunct to diet is specifically indicated for: 1) Co-administration Therapy with Statins for the Treatment of Mixed Dyslipidemia To reduce TG and increase HDLC in patients with mixed dyslipidemia and CHD or a CHD risk equivalent who are on optimal statin therapy to achieve their LDL-C goal. 2) Treatment of Severe Hypertriglyceridemia To reduce TG ...
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4.  Study Posting (709) Trial #50652, Alzheimer's Disease, Palo Alto, CA
...research study to investigate the safety and effectiveness of simvastatin (a cholesterol lowering drug or statin) to slow the progression of Alzheimer’s disease (AD). Statins are commonly used to treat high cholesterol levels, which increase the risk of heart disease ...
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5.  Newly Approved Drug Therapies (976) Welchol (colesevelam hydrochloride), Daiichi Sankyo,
...percent change in serum LDL-C levels with Welchol compared to placebo was -16% among statin users and statin non-users; the median percent change in serum TG levels with Welchol compared to placebo ...
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6.  Study Posting (811) Trial #152706, Atherosclerosis, New York, NY
...over a 12 week period in subjects with established atherosclerosis who are on a stable statin dose. Your participation in this study will last for approximately 12weeks. You will first be ...
...ascending aorta plaque inflammation defined as TBR = 1.6] • On a stable dose of a Statin for 3 months prior to screening with no evidence of Statin intolerance. Patient Exclusion Criteria ...
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7.  Study Posting (577) Trial #127145, High Cholesterol (Hyperlipidemia), Richmond, VA
...If you have High Cholesterol If you have high cholesterol and have been taking a statin drug such as Lipitor, Zocor, Crestor or Simvastatin for at least 3 months, you may ...
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8.  Study Posting (1955) Trial #154770, Heart Disease, Haverhill, MA
...High Cholesterol Age 50-80 with a history of cardiovascular issues. Must be on a Statin 3 months or more. No cost MRI/PET scan are part of the screening tests ...
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9.  Study Posting (1955) Trial #154771, High Cholesterol (Hyperlipidemia), Haverhill, MA
...High Cholesterol Age 50-80 with a history of cardiovascular issues. Must be on a Statin 3 months or more. No cost MRI/PET scan are part of the screening tests ...
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10.  Study Posting (5194) Trial #85513, Heart Disease, Walnut Creek, CA
...know that high cholesterol can increase your risk of heart attacks or strokes, and that statin medications can help lower high cholesterol. Doctors and scientists know now that inflammation in the ...
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11.  Study Posting (2040) Trial #95988, Coronary Artery Disease, Fort Lauderdale, FL
...disease subjects beyond the known benefits of simvastatin monotherapy. Several Study Inclusion Criteria Include: • A statin-naïve subject will be eligible to enroll if his/her LDL-C concentration is = 50 mg/dL and =125 mg/dL; • A subject receiving chronic statin therapy will be eligible to enroll, if his/her LDL-C concentration is = 50 mg ...
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12.  Study Posting (1570) Trial #156480, Coronary Artery Disease, Morristown, NJ
...acute coronary syndrome (either STEMI or Non-STEMI or unstable angina) • Subjects not taking a statin must have an LDL-C of 125 mg/dl or less. Subjects taking a statin must have an LDL-C of 100 mg/dl or less. Patient Exclusion Criteria: • Pregnant ...
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13.  Study Posting (1955) Trial #149635, High Cholesterol (Hyperlipidemia), Haverhill, MA
...of an oral investigational medication for subjects who have cardiac issues and take only 1 statin medication for high cholesterol. PET scan and MRI will be taken to determine plaque inflammation ...
...but stable for the last 6 months or longer. • Subjects need to be taking one statin medication for high cholesterol at a stable dose for the past 3 months. • Elevated plaque ...
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14.  Study Posting (5234) Trial #158693, Coronary Artery Disease, Miami, FL
...in high risk hypercholesterolemic patients. treating hypercholesterolemic patients who are a maximally tolerated dose of statin and who have a diagnosis that puts them at a high risk odf coronary heart ...
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15.  CenterWatch: New Medical Therapies in Disease Category (170), High Cholesterol (Hyperlipidemia)
...subjects, 10-17 years of age, who were either treatment nave or on stable background statin therapy. The study consisted of an initial four-week, single-blind, placebo run-in, to ...
...cholesterol from baseline was statistically significant (8.4%) in the high dose group. Subjects taking statins, however, did not show significant changes in HDL-cholesterol. The placebo controlled, six-month study ...
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16.  Study Posting (5437) Trial #158297, Heart Disease, San Ramon, CA
...post-menopausal or using a highly effective method for avoidance of pregnancy. • Current treatment with statin therapy unless the study doctor determines statins are not appropriate for the subject. • Chronic coronary heart disease • At least one of the ...
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17.  Newly Approved Drug Therapies (1048) Livalo (pitavastatin), Kowa Company,
...mixed dyslipidemia General Information Livalo is a HMG-CoA reductase inhibitor. It differs from other statins in that it has a unique cyclopropyl group on the base structure. This cyclopropyl group ...
...extremity Mechanism of Action Livalo is a HMG-CoA reductase inhibitor. It differs from other statins in that it has a unique cyclopropyl group on the base structure. This cyclopropyl group ...
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18.  Newly Approved Drug Therapies (839) Crestor (rosuvastatin calcium), AstraZeneca,
...lipid-lowering agent approved as a treatment for hypercholesterolemia. The drug is classified as a Statin, a type of agent that inhibits cholesterol production in the liver. Crestor is indicated as ...
...in high-density lipoprotein cholesterol (HDL-C.) Literature References Davidson MH. . Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. Expert Opin Investig Drugs . 2002 Mar;11(3):125-41 ...
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19.  Study Posting (799) Trial #161735, High Cholesterol (Hyperlipidemia), Boston, MA
...Disease ( Cholesterol build-up or hardening of the arteries ), currently taking any of the following statin drugs for at least 4 weeks: Atorvastatin 10 mg, Simvastatin 40 mg, Pravastatin 40 mg ...
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20.  Newly Approved Drug Therapies (302) Baycol (cerivastatin sodium), Bayer,
...cholesterol-lowering agent by Bayer Corporation, was initially FDA approved in 1997. Baycol is a statin indicated as an adjunct to diet for patients with primary hypercholesterolemia and mixed dyslipidemia who ...
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