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1.  Study Posting (266) Trial #109267, High Cholesterol (Hyperlipidemia), Stamford, CT
...65 or over with high cholesterol? Researchers want to find out if a drug called ezetimibe (Zetia) can help people with high cholesterol who are at high risk for heart disease. The purpose of this study is to give ezetimibe to some people to see if it is safe and can help them when taken ...
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2.  Study Posting (4561) Trial #154286, High Cholesterol (Hyperlipidemia), Oviedo, FL
...Oviedo, FL Trial Information A study to determine if a combination of rosuvastatin (Crestor) and ezetimibe (Zetia) works better at lowering cholesterol than rosuvastatin alone. A study to determine if a combination of rosuvastatin (Crestor) and ezetimibe (Zetia) works better at lowering cholesterol than rosuvastatin alone. The safety of this investigational combination ...
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3.  Study Posting (2040) Trial #95988, Coronary Artery Disease, Fort Lauderdale, FL
...Fort Lauderdale, FL Trial Information Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting with Acute Coronary Syndrome. The intent of this clinical study is to demonstrate the benefit of Ezetimibe/Simvastatin combination over at least 2.5 years of follow-up in high-risk coronary ...
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4.  Study Posting (1570) Trial #156480, Coronary Artery Disease, Morristown, NJ
...Morristown, NJ Trial Information IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (Study P04103AM3) A Multicenter, Double-Blind, Randomized Study to Establish the Clinical ...
...serum transaminase elevation • History of alcohol or drug abuse • History of sensitivity to statin or ezetimibe • A subject for whom discontinuation of existing lipid lowering regimen poses an unacceptable risk. Kelly ...
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5.  CenterWatch: New Medical Therapies in Disease Category (48), Congenital Heart Disease
...Hypercholesterolemia (HeFH). This multinational, randomized, double-blind, active comparator trial, dubbed ENHANCE (Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous ...
...seven hundred and twenty subjects with HeFH. The subjects were randomized to Vytorin (10 mg ezetimibe + 80 mg simvastatin) or simvastatin alone (80 mg) for two years. There was no statistically ...
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6.  Study Posting (748) Trial #150206, High Cholesterol (Hyperlipidemia), Harrisburg, NC
...not Adequately Controlled with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg The purpose of ...
...not Adequately Controlled with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg High Cholesterol (Hyperlipidemia ...
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7.  CenterWatch: New Medical Therapies in Disease Category (170), High Cholesterol (Hyperlipidemia)
...Hypercholesterolemia (HeFH). This multinational, randomized, double-blind, active comparator trial, dubbed ENHANCE (Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous ...
...seven hundred and twenty subjects with HeFH. The subjects were randomized to Vytorin (10 mg ezetimibe + 80 mg simvastatin) or simvastatin alone (80 mg) for two years. There was no statistically ...
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8.  Study Posting (77) Trial #156845, High Cholesterol (Hyperlipidemia), Great Neck, NY
...Have a known allergy (hypersensitivity) to or other reason not to take the study drug (ezetimibe) • Are pregnant or breastfeeding • Have a disease likely to limit life span to less than ...
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9.  CenterWatch: Clinical Trials in Category (170) High Cholesterol (Hyperlipidemia)
...Oviedo : Alpha Medical Research A study to determine if a combination of rosuvastatin (Crestor) and ezetimibe (Zetia) works better at lowering cholesterol than rosuvastatin alone. Oviedo : Alpha Medical Research Treatment of ...
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10.  CenterWatch Clinical Research Profile (2040) Trial #1007, Holy Cross Hospital Research Center, Ft. Lauderdale, FL
...Occluded Central Venous Access Devices. • Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting with Acute Coronary Syndrome. • Study ...
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11.  Newly Approved Drug Therapies (976) Welchol (colesevelam hydrochloride), Daiichi Sankyo,
...2 diabetes. Clinical therapeutics 2007 Jan;29(1):74-83 Zema MJ Colesevelam HCl and ezetimibe combination therapy provides effective lipid-lowering in difficult-to-treat patients with hypercholesterolemia. American Journal ...
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12.  CenterWatch: Clinical Trials in Category (50) Coronary Artery Disease
...Holy Cross Hospital Research Center Study to Establish the Clinical Benefit and Safety of Vytorin (Ezetimibe/Simvastatin Tablet) vs Simvastatin Monotherapy in High-Risk Subjects Presenting with Acute Coronary Syndrome. Ft ...
...Morristown : Atlantic Health System IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (Study P04103AM3) Morristown : Atlantic Health System Protect II, A Prospective, Multicenter Randomized ...
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13.  CenterWatch Clinical Research Profile (4561) Trial #1915, Alpha Medical Research, Oviedo, FL
...Diabetes is being conducted. • A study to determine if a combination of rosuvastatin (Crestor) and ezetimibe (Zetia) works better at lowering cholesterol than rosuvastatin alone. • An Osteoarthritis study, GI-REASONS, (Gastro ...
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14.  CenterWatch Clinical Research Profile (1570) Trial #819, Atlantic Health System, Morristown, NJ
...Biologicals HPV-16/18 • IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (Study P04103AM3) • Natural History Study of the Development of Type 1 Diabetes ...
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15.  CenterWatch: New Medical Therapies in Disease Category (50), Coronary Artery Disease
...CV Therapeutics and Fujisawa Healthcare . March 25, 2002 Phase III trial results indicate that Zetia (ezetimibe) provides additional reductions in LDL-C when co-administered with a statin. All subjects in ...
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