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1. Study Posting (5234) Trial #158711, Hypertension (High Blood Pressure), Miami, FL ...such as volume and salt depletion • participation in another clinical trial • evidence of symptomatic resting bradycardia • evidence of liver disease • known allergy to any medication used in the studywell Well Pharma ...View Page
2. Newly Approved Drug Therapies (470) Marplan Tablets, Roche, ...include: headaches, palpitation, neck stiffness, nausea or vomiting, sweating (fevers or clammy skin), photophobia, tachycardia, bradycardia, constricting chest pain, dilated pupils, intracranial bleeding and increased blood pressure. Jobson Medical Information • Privacy ...View Page
3. Study Posting (466) Trial #157645, Migraine and Cluster Headaches, Providence, RI ...psychiatric disorder • Contraindication to or prior intolerance of topiramate or propranolol (no history of sinus bradycardia, heart block, heart failure, diabetes prone to hypoglycemia, asthma, kidney stones) • History of kidney failure ...View Page
4. Study Posting (466) Trial #157647, Migraine and Cluster Headaches, Bellingham, MA ...psychiatric disorder • Contraindication to or prior intolerance of topiramate or propranolol (no history of sinus bradycardia, heart block, heart failure, diabetes prone to hypoglycemia, asthma, kidney stones) • History of kidney failure ...View Page
5. Study Posting (466) Trial #157646, Migraine and Cluster Headaches, Pawcatuck, CT ...psychiatric disorder • Contraindication to or prior intolerance of topiramate or propranolol (no history of sinus bradycardia, heart block, heart failure, diabetes prone to hypoglycemia, asthma, kidney stones) • History of kidney failure ...View Page
6. Newly Approved Drug Therapies (452) Infasurf, ONY, ...Infasurf. Side Effects The most common side effects occurring with Infasurf were: cyanosis, airway obstruction, bradycardia, reflux of surfactant into the endotracheal tube, requirement for manual vantilation and reintubation. These events ...View Page
7. Newly Approved Drug Therapies (460) Thalomid, Celgene, ...and somnolence, peripheral neuropathy, dizziness and orthostatic hypotension, neutropenia, increased HIV-Viral load, hypersensitivity and Bradycardia. It has also been reported to enhance the sedative activity of barbituates, alcohol, chlorpromazine and ...View Page
8. Newly Approved Drug Therapies (602) Betapace AF Tablet, Berlex Laboratories, ...TdP). Patients taking this drug should be monitored carefully with electrocardiogram. Side effects may include: • Bradycardia • Fatigue • Fainting • Dizziness • Tachycardia • Severe diarrhea • Unusual sweating • Vomiting • Decreased appetite • Increased thirst Contraindications to ......chronic renal failure • chronic lung disease (such as asthma, chronic bronchitis, or emphysema) • heart failure • bradycardia Mechanism of Action Betapace AF (sotalol hydrochloride) has both beta-andrenoreceptor blocking (Vaughan Williams Class ...View Page
9. Newly Approved Drug Therapies (601) Betaxon, Alcon, ...may include: • Severe respiratory reactions • Severe cardiac reactions Betaxon is contraindicated in patients with sinus bradycardia, greater than a first degree atrioventricular block, cardiogenic shock, or patients with over cardiac failure ...View Page
10. Newly Approved Drug Therapies (600) Evoxac, SnowBrand Pharmaceuticals, ...Headache • Visual disturbance • Lacrimation • Sweating • Respiratory distress • Gastrointestinal spasm • Nausea • Vomiting • Diarrhea • Atrioventricular block • Tachycardia • Bradycardia • Hypotension • Hypertension • Shock • Mental confusion • Cardiac arrhythmia • Tremors Since the active ingredient, cevimeline, may cause ...View Page
11. Newly Approved Drug Therapies (715) Natrecor (nesiritide), Scios, ...limited to) the following: • Hypotension • Ventricular tachycardia (abnormally fast heart rate) • Angina pectoris (chest pain) • Bradycardia (abnormally slow heart rate) • Headache • Abdominal pain • Back pain • Insomnia • Dizziness • Anxiety • Nausea • Vomiting Mechanism ...View Page
12. Newly Approved Drug Therapies (770) SecreFlo (secretin), Repligen, ...trials of SecreFlo include (but are not limited to) the following: • Abdominal discomfort • Nausea • Mild bradycardia (reduced heart rate) • Decreased blood pressure • Diaphoresis (profuse perspiration) Mechanism of Action SecreFlo (secretin) is ...View Page
13. Newly Approved Drug Therapies (1036) Multaq (dronedarone), Sanofi-aventis, ...but are not limited to, the following: • Diarrhea • Asthenic conditions • Nausea • Skin infections • Abdominal pain • Bradycardia Mechanism of Action Multaq (dronedarone) is a benzofuran derivative with antiarrhythmic properties belonging to all ...View Page
14. Clinical Trial Results by Drug Names ...serious adverse events. Apart from the previously mentioned death, 1 other serious adverse event, sinus bradycardia in a patient in the placebo group, was considered related to study treatment by the ...View Page
15. Clinical Trial Results by Drug Names ...associated with the use of beta-blockers, such as worsening heart failure, symptomatic hypotension or bradycardia, no significant differences were found between age groups. Conclusions: Dilatrend appeared to be well tolerated ...View Page
16. Clinical Trial Results by Drug Names ...3.6%) occurred more frequently with metoprolol. No consistent differences were seen with regard to bradycardia or heart block. Hypotension (14.2% vs 10.4%), dizziness (12.2% vs 11.3% ...View Page
17. Clinical Trial Results by Drug Names ...of 5 AEs between Days 1 and 3. All AEs were mild (constipation) or moderate (bradycardia, palpitations, headache, and fatigue) in intensity and considered unrelated to trial treatment, except for constipation ...View Page
18. Newly Approved Drug Therapies (895) Myozyme (alglucosidase alfa), Genzyme, ...with cardiac hypertrophy has been associated with cardiac arrhythmia, including ventricular fibrillation, ventricular tachycardia and bradycardia, resulting in cardiac arrest or death, or requiring cardiac resuscitation or defibrillation. Appropriate caution and ...View Page
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