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1.  Study Posting (2246) Trial #117754, Fungal Infections, Duarte, CA
...Study Posting (2246) Trial #117754, Fungal Infections, Duarte, CA Trial Information Fungal Antigens and Antifungal Response For the Patients S uspected or Diagnosed with Aspergillosis   You have been asked to ...
...you are a healthy adult. The purpose of this research is to study naturally occurring antifungal antibodies and T-cells in humans in order to further understanding of antifungal immunity. Your ...
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2.  CenterWatch: New Medical Therapies in Disease Category (143), Systemic Fungal Infections
...reported positive results from a phase III trial investigating NOXAFIL (posaconazole suspension) , a broad-spectrum antifungal for the treatment of invasive fungal infections. Results showed subjects successfully met the study's ...
...response. The study enrolled 337 subjects with invasive fungal infections resistant or refractory to standard antifungal therapies. The company expects to submit an NDA shortly for NOXAFIL to the FDA and ...
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3.  Newly Approved Drug Therapies (696) Cancidas, Merck,
...Life-threatening fungal infections General Information Cancidas is the first in a new class of antifungals, called echinocandins, to be introduced in more than a decade. This medication is approved for the intravenous treatment of invasive aspergillosis in patients who have not responded to standard antifungal therapies. Aspergillosis is a life-threatening fungal infection most commonly seen in cancer patients, organ ...
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4.  Newly Approved Drug Therapies (908) Noxafil (posaconazole), Schering-Plough,
...Approved in September 2006 Treatment Area: Fungal infections General Information Noxafil (posaconazole) is a triazole antifungal agent. It blocks the synthesis of ergosterol, a key component of the fungal cell membrane ...
...2011 • Schering has agreed to a post approval study to be conducted among patients receiving antifungal prophylaxis. The study will enroll patients who are at risk for low absorption. Different dosing ...
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5.  CenterWatch: New Medical Therapies in Disease Category (625), Eczema (Atopic Dermatitis - Pediatric)
...16, 2004 Barrier Therapeutics reported results from a phase III trial investigating Zimycan , a topical antifungal ointment for the treatment of Candida-associated diaper dermatitis. Results showed that Zimycan achieved statistical ...
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6.  CenterWatch: Clinical Trials in Category (66) Fungal Infections
...Tuscon Clinical Research Study: Toenail Fungus California Duarte : City of Hope New! Fungal Antigens and Antifungal Response Colorado Longmont : Longmont Medical Research Network TOENAIL FUNGUS (ONYCHOMYCOSIS) Florida Pinellas Park : Radiant Research ...
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7.  Newly Approved Drug Therapies (954) Extina (ketoconazole), Stiefel,
...June 2007 Treatment Area: seborrheic dermatitis General Information Extina foam contains 2% ketoconazole USP, an antifungal agent. The mechanism of action of ketoconazole in the treatment of seborrheic dermatitis is not ...
...Irritation • Paresthesia • Pruritus • Rash • Warmth Mechanism of Action Extina foam contains 2% ketoconazole USP, an antifungal agent. The mechanism of action of ketoconazole in the treatment of seborrheic dermatitis is not ...
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8.  Newly Approved Drug Therapies (953) Torisel (temsirolimus), Wyeth,
...renal cell carcinoma General Information Torisel is a derivative of rapamycin, an agent that exhibits antifungal, immunosuppressant and antitumor activities. Torisel appears to block the effects of mTOR, an enzyme that ...
...Edema • Anorexia Mechanism of Action Torisel is a derivative of rapamycin, an agent that exhibits antifungal, immunosuppressant and antitumor activities. Torisel appears to block the effects of mTOR, an enzyme that ...
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9.  Newly Approved Drug Therapies (85) Mentax (1% butenafine HCI cream), Penederm,
...topical treatment of athlete's foot. Butenafine is the first of a new class of antifungal agents known as the benzylamines, which are chemically and pharmacologically related to the allylamine antifungal drugs. Jobson Medical Information • Privacy | • Glossary Copyright © 1995-2010 Jobson Medical Information LLC. Designed by ...
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10.  Newly Approved Drug Therapies (691) Lamisil Solution, 1%, Novartis,
...Approved March 2001 Treatment Area: Dermatologic infections General Information Lamisil Solution, 1% is a synthetic antifungal compound approved for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur, and ...
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11.  Study Posting (1570) Trial #156498, Candidemia/Candidiasis, Morristown, NJ
...or systemic amphotericin B product • Infant who has received more than 48 hours of systemic antifungal therapy prior to the first dose of study drug • Infant who has a breakthrough systemic ...
...receiving amphotericin B product or an echinocandin as prophylaxis • Infant who has failed prior systemic antifungal therapy for this episode of invasive candidiasis • Infant who is co-infected with a non ...
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12.  Newly Approved Drug Therapies (661) Lotrisone (clotrimazole/betamethasone diproprionate) lotion, Schering-Plough,
...and Trichophyton rubrum . Lotrisone contains two compounds - a synthetic corticosteroid (betamethasone dipropionate) and a synthetic antifungal agent (clotrimazole) - that target different aspects of fungal infection. Clotrimazole targets the cause of the ...
...Burning • Excessive hair growth • Inflamed hair follicles Mechanism of Action Clotrimazole is a broad-spectrum, antifungal agent used for the treatment of superficial infections caused by species of pathogenic dermatophytes, yeasts ...
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13.  Newly Approved Drug Therapies (27) Femstat 3 (butoconazole nitrate 2%), Procter & Gamble, Roche,
...be the first 3-day treatment brand available without a prescription. Femstat 3 contains the antifungal agent butoconazole nitrate, which was developed specifically for the local treatment of vaginal yeast infections ...
...studies included 3,267 subjects treated with butoconazole nitrate; 1,735 subjects treated with other antifungal agents; and 287 subjects treated with a placebo. In these 45 studies, the drug-related ...
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14.  Newly Approved Drug Therapies (350) Mentax (1% butenafine HCl cream), Penederm,
...for four weeks for more severe cases of the fungus. Mentax is the only topical antifungal product approved in the U.S. which has such a one-week dosing regimen. Jobson ...
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15.  Study Posting (2246) Trial #153431, Solid Tumors, Duarte, CA
...as Aspergillus. The purpose of this study is to compare treatment with a combination of antifungal medicines (voriconazole and anidulafungin) to treatment with voriconazole alone. Your/your child's participation in ...
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16.  CenterWatch Clinical Research Profile (430) Trial #690, Radiant Research - St. Petersburg, Pinellas Park, FL
...in database : 18,800+ Regulatory submission : 3 business days Areas of Experience: • Acne • Actinic Keratosis • Antifungals • Antimicrobials • Atopic Dermatitis • Bronchitis – Acute • Bronchitis – Chronic • Contraception • Diabetes Type II • Dry Eye • Eczema • Endometrial ...
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17.  CenterWatch: New Medical Therapies in Disease Category (332), Systemic Candidiasis
...Schering-Plough reported positive results from a case series investigating Noxafil ( posaconazole oral suspension ), an antifungal agent for the treatment of coccidioidomycosis. Results showed that all subjects initially received benefit from ...
...six subjects and was designed to test the efficacy and safety of Noxafil, after standard antifungal therapies have failed. Results were presented at the 41st annual meeting of the Infectious Diseases ...
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18.  Study Posting (5265) Trial #147145, Pleural Diseases, Hoddesdon, United Kingdom
...weeks of the start of study drug, or had treatment with intravenous antibiotic, antiviral, or antifungal medications within 2 weeks of the start of study drug. • Patient is pregnant or breast ...
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19.  Study Posting (5265) Trial #147143, Pleural Diseases, Sollentuna, Sweden
...weeks of the start of study drug, or had treatment with intravenous antibiotic, antiviral, or antifungal medications within 2 weeks of the start of study drug. • Patient is pregnant or breast ...
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20.  Study Posting (5265) Trial #147141, Pleural Diseases, Madrid, Spain
...weeks of the start of study drug, or had treatment with intravenous antibiotic, antiviral, or antifungal medications within 2 weeks of the start of study drug. • Patient is pregnant or breast ...
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